Motoichi Kurisawa Selected Research

Neoplasms (Cancer)

12/2019	A two-pronged anti-leukemic agent based on a hyaluronic acid-green tea catechin conjugate for inducing targeted cell death and terminal differentiation.
10/2019	Mechanically and chemically defined hydrogel matrices for patient-derived colorectal tumor organoid culture.
1/2019	Hyaluronic acid hydrogels with defined crosslink density for the efficient enrichment of breast cancer stem cells.
1/2019	Carrier-Enhanced Anticancer Efficacy of Sunitinib-Loaded Green Tea-Based Micellar Nanocomplex beyond Tumor-Targeted Delivery.
4/2018	Highly Augmented Drug Loading and Stability of Micellar Nanocomplexes Composed of Doxorubicin and Poly(ethylene glycol)-Green Tea Catechin Conjugate for Cancer Therapy.
12/2017	Hyaluronic acid-green tea catechin micellar nanocomplexes: Fail-safe cisplatin nanomedicine for the treatment of ovarian cancer without off-target toxicity.
3/2016	Targeted intracellular protein delivery based on hyaluronic acid-green tea catechin nanogels.
10/2015	Hyaluronidase-incorporated hyaluronic acid-tyramine hydrogels for the sustained release of trastuzumab.
11/2014	Self-assembled micellar nanocomplexes comprising green tea catechin derivatives and protein drugs for cancer therapy.
3/2013	Injectable hyaluronic acid-tyramine hydrogels incorporating interferon-α2a for liver cancer therapy.

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Motoichi Kurisawa Research Topics

Disease

11	Neoplasms (Cancer) 12/2019 - 01/2007
2	Inflammation (Inflammations) 11/2018 - 10/2017
2	Wounds and Injuries (Trauma) 04/2012 - 01/2012
1	Rheumatoid Arthritis 04/2021
1	Shock 11/2020
1	Cerebral Hemorrhage 01/2020
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2019
1	Colorectal Neoplasms (Colorectal Cancer) 10/2019
1	Hypoxia (Hypoxemia) 10/2019
1	Breast Neoplasms (Breast Cancer) 01/2019
1	Ovarian Neoplasms (Ovarian Cancer) 12/2017
1	Colonic Neoplasms (Colon Cancer) 03/2016
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2016
1	Hepatitis C 09/2015
1	Liver Neoplasms (Liver Cancer) 03/2013
1	Contracture 05/2012
1	Gout 02/2004

Drug/Important Bio-Agent (IBA)

11	HydrogelsIBA 01/2020 - 01/2012
6	TeaIBA 04/2021 - 11/2014
6	Hyaluronic Acid (Hyaluronan)IBA 04/2021 - 03/2013
4	Catechin (Z 7300)IBA 04/2021 - 11/2014
3	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 04/2021 - 02/2004
3	GelatinIBA 11/2020 - 10/2019
3	Pharmaceutical PreparationsIBA 01/2019 - 04/2018
3	TyramineIBA 10/2017 - 03/2013
2	Ethylene Glycol (Monoethylene Glycol)IBA 04/2018 - 01/2007
2	Proteins (Proteins, Gene)FDA Link 03/2016 - 11/2014
2	InterferonsIBA 01/2016 - 09/2015
2	SolutionsIBA 10/2015 - 03/2013
1	Interleukin-6 (Interleukin 6)IBA 04/2021
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2020
1	Epidermal Growth Factor (EGF)IBA 01/2020
1	MicellesIBA 01/2019
1	monomethoxypolyethyleneglycol- polylactide block copolymerIBA 01/2019
1	Sunitinib (Sutent)FDA Link 01/2019
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2019
1	poly(lactide) (polylactic acid)IBA 01/2019
1	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2018
1	Cisplatin (Platino)FDA LinkGeneric 12/2017
1	PolyethyleneimineIBA 03/2016
1	polyethylene glycol polyethyleneimine nanogelIBA 03/2016
1	Granzymes (Granzyme)IBA 03/2016
1	NanogelsIBA 03/2016
1	Interferon-alpha (Interferon Alfa)IBA 01/2016
1	Sorafenib (BAY 43-9006)FDA Link 01/2016
1	Hyaluronoglucosaminidase (Hyaluronidase)FDA Link 10/2015
1	Trastuzumab (Herceptin)FDA Link 10/2015
1	Caspase 3 (Caspase-3)IBA 03/2013
1	DNA (Deoxyribonucleic Acid)IBA 01/2007
1	ChitosanIBA 01/2007
1	PEG-graft-trimethyl-chitosan copolymerIBA 01/2007
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2007
1	Superoxides (Superoxide)IBA 02/2004
1	AntioxidantsIBA 02/2004
1	Xanthine OxidaseIBA 02/2004

Therapy/Procedure

10	Therapeutics 04/2021 - 03/2013
6	Injections 11/2020 - 01/2012
2	Subcutaneous Injections 11/2018 - 10/2015
1	Drug Therapy (Chemotherapy) 12/2019
1	Immunotherapy 01/2016